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Population genomics of Group B Streptococcus reveals the genetics of neonatal disease onset and meningeal invasion

21 Jul 2022

Abstract excerpt

Group B Streptococcus (GBS), or Streptococcus agalactiae, is a pathogen that causes preterm births, stillbirths, and acute invasive neonatal disease burden and mortality. Here, we investigate bacterial genetic signatures associated with disease onset time and meningeal tissue infection in acute invasive neonatal GBS disease. We carry out a genome-wide association study (GWAS) of 1,338 GBS isolates from newborns...

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PMID: 35864107
DOI: 10.1038/s41467-022-31858-4

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