Article

LacR and TrxB are key virulence factors involved in pneumococcal meningitis as identified by a genome-wide association study

2025-06-27

Abstract excerpt

<title>Abstract</title> Pneumococcal meningitis is the most common form of bacterial meningitis, with high case fatality rates. Bacterial genetics influence disease severity and patient outcome, but the mechanisms underlying pneumococcal meningitis pathogenesis remain poorly understood. Here, we evaluated top variants from a genome-wide association study (GWAS) linking Streptococcus pneumoniae genetic variatio...

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Literature Corpus work: d1d96114-64af-55da-9cc0-3f9811e62e2f
DOI: 10.21203/rs.3.rs-6771075/v1

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