Article

Silica-mediated exacerbation of inflammatory arthritis: A novel murine model

2025-01-10

Abstract excerpt

<h4>Objective</h4> The mucosal origin hypothesis in rheumatoid arthritis (RA) posits that inhalant exposures, such as cigarette smoke and crystalline silica (c-silica), trigger immune responses contributing to disease onset. Despite the established risk posed by these exposures, the mechanistic link between inhalants, lung inflammation, and inflammatory arthritis remains poorly understood, partly from the lack of...

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Literature Corpus work: fddb3f25-c5e5-55fe-ba1f-5247357c2e71
DOI: 10.1101/2025.01.07.631488

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