Article
One year in review 2017: pathogenesis of rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Angelotti Francesca, Parma Alice, Cafaro Giacomo, Capecchi Riccardo, Alunno Alessia, Puxeddu Ilaria
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both genetic and environmental factors. It has been postulated that a high-risk genetic background, in combination with epigenetic marks and environmental exposures, leads to a cascade of events inducing synovitis and consequent destructive arthritis. The clinical picture of joint involvement in RA is the result of chronic...
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