Article

Identification of candidate causal <i>cis</i> -regulatory variants underlying electrocardiographic QT interval GWAS loci

2024-03-15

Abstract excerpt

Identifying causal variants among tens or hundreds of associated variants at each locus mapped by genome-wide association studies (GWAS) of complex traits is a challenge. As vast majority of GWAS variants are noncoding, sequence variation at cis -regulatory elements affecting transcriptional expression of specific genes is a widely accepted molecular hypothesis. Following this cis -regulatory hypothesis and comb...

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Literature Corpus work: fdd484f7-c704-5443-8ec6-f98fb4700301
DOI: 10.1101/2024.03.13.584880

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