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Development of 3D breast cancer models with human T cells expressing engineered MAIT cell receptors

2022-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Immunotherapy has revolutionized cancer treatment with the advent of advanced cell engineering techniques aimed at targeted therapy with reduced systemic toxicity. However, understanding the underlying immune-cancer interactions require development of advanced three-dimensional (3D) models of human tissues. In this study, we developed proof-of-concept 3D tumor models with increasing complexity t...

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Literature Corpus work
fd9dc458-97a9-5d22-a825-44178a43630d
DOI
10.1101/2022.01.29.478309
Open publication

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Development of 3D breast cancer models with human T cells expressing engineered MAIT cell receptorsDOI 10.1101/2022.01.29.478309
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