Article

Temporal Changes in Immune Responses within the Tumor Microenvironment in the 4T1.2-HER2 Mammary Tumor Model

2021-02-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The murine 4T1.2 triple-negative breast cancer model is widely used, but is poorly immunogenic with no defined tumor-associated antigens. A modified 4T1.2 model has been developed that stably expresses a surrogate tumor antigen, human epidermal growth factor receptor-2 (HER2). The goal of the current study was to characterize host immune responses in the 4T1.2-H...

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Literature Corpus work: 9018ea75-07a4-52f0-ba1c-7714c9d3b7e0
DOI: 10.21203/rs.3.rs-180530/v1

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