Article

Mesothelin- and nucleolin-specific T cells from combined short peptides effectively kill triple-negative breast cancer cells

2024-04-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Triple-negative breast cancer (TNBC), known for its aggressiveness and limited treatment options, presents a significant challenge. Adoptive cell transfer, involving the <italic>ex vivo</italic> generation of antigen-specific T cells from peripheral blood mononuclear cells (PBMCs), emerges as a promising approach. The overexpression of mesothelin (MSLN) and nucle...

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Literature Corpus work: 3211e16b-270b-5d29-a4fe-6289ffd0e401
DOI: 10.21203/rs.3.rs-4289025/v1

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