Article

Inference and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis

2019-12-06

Abstract excerpt

<h4>Background</h4> Hypothesis-free Mendelian randomization studies provide a way to assess the causal relevance of a trait across the human phenome but can be limited by statistical power or complicated by horizontal pleiotropy. The recently described latent causal variable (LCV) approach provides an alternative method for causal inference which might be useful in hypothesis-free experiments. <h4>Methods</h4> W...

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Literature Corpus work: fd8a722f-c426-5b6b-8b4e-cff0f530f855
DOI: 10.1101/865956

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