Article

Synaptic changes in pallidostriatal circuits observed in parkinsonian model triggers abnormal beta synchrony with accurate spatio-temporal properties across the basal ganglia

2023-03-10

Abstract excerpt

Excessive oscillatory activity across basal ganglia (BG) nuclei in the β frequencies (12–30Hz) is a hallmark of Parkinson’s disease (PD). While the link between oscillations and symptoms remains debated, exaggerated β oscillations constitute an important biomarker for therapeutic effectiveness in PD. The neuronal mechanisms of β- oscillation generation however remain unknown. Many existing models rely on a cent...

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Literature Corpus work: fd8482bf-b3ff-5ff4-b24b-4822ad3a695d
DOI: 10.1101/2023.03.07.531640

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Synaptic changes in pallidostriatal circuits observed in parkinsonian model triggers abnormal beta synchrony with accurate spatio-temporal properties across the basal gangliaDOI 10.1101/2023.03.07.531640Read

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