Article

Propagation of Beta/Gamma Rhythms in the Cortico-Basal Ganglia Circuits of the Parkinsonian Rat

2017-08-24

Abstract excerpt

Some motor impairments associated with Parkinson’s disease are thought to arise from pathological activity in the neuronal networks formed by the basal ganglia (BG) and motor cortex. To evaluate several hypotheses proposed to explain the emergence of pathological oscillations in Parkinsonism, we investigated changes to the directed connectivity in these networks following dopamine depletion. We recorded local fiel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de101ebf-82b9-5b82-870d-cb5d90ab8eb0
DOI: 10.1101/180455

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Propagation of Beta/Gamma Rhythms in the Cortico-Basal Ganglia Circuits of the Parkinsonian RatDOI 10.1101/180455Read

Synaptic changes in pallidostriatal circuits observed in parkinsonian model triggers abnormal beta synchrony with accurate spatio-temporal properties across the basal gangliaSemantic proximity Read

Neural signatures of pathological hyperdirect pathway activity in Parkinson’s diseaseSemantic proximity Read

Beta-Band Oscillations without Segregated Pathways: the opposing Roles of D2 and D5 Receptors in the Basal GangliaSemantic proximity Read

Sensorimotor processing in the basal ganglia leads to transient beta oscillations during behaviorSemantic proximity Read

Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta bandSemantic proximity Read

Aberrant striatal oscillations after dopamine loss in parkinsonian non-human primatesSemantic proximity Read

Thalamocortical dynamics underlying spontaneous transitions in beta power in ParkinsonismSemantic proximity Read

Coupled beta and high-frequency oscillations emerge from synchronized bursting in a minimal model of the parkinsonian subthalamic nucleusSemantic proximity Read

Network mechanisms in rapid-onset dystonia-parkinsonismSemantic proximity Read

Autonomous oscillations and phase-locking in a biophysically detailed model of the STN-GPe networkSemantic proximity Read

Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson's patientsSemantic proximity Read

Mechanistic insights into neuronal oscillatory activity in the dopamine-intact and dopamine-depleted primary motor cortexSemantic proximity Read