Article

Gamma oscillations in basal ganglia stem from the interplay between local inhibition and beta synchronization

2025-03-19

Abstract excerpt

Basal ganglia rhythms have mainly been studied in the beta band (12-30 Hz), a hallmark of Parkinson's disease (PD), while gamma oscillations (30-100 Hz) in the subthalamic nucleus (STN) have emerged as alternative markers for guiding adaptive deep brain stimulation. However, their underlying mechanisms remain unclear. Using a spiking network model of the basal ganglia, we identified two distinct gamma rhythms: a h...

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Literature Corpus work: de314c74-50d9-52c7-9e32-2267ac6dbfbe
DOI: 10.1101/2025.03.19.644161

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