Article
Shared and unique imaging-derived endo-phenotypes of two typical antidepressant-applicative depressive patients.
European radiology - 1 Jan 2023
Xue Li, Shao Junneng, Wang Huan, Wang Xinyi, Zhu Rongxin, Yao Zhijian, Lu Qing
Abstract excerpt
OBJECTIVES: Determining the clinical homogeneous and heterogeneous sets among depressive patients is the key to facilitate individual-level treatment decision. METHODS: The diffusion tensor imaging (DTI) data of 62 patients with major depressive disorder (MDD) and 39 healthy controls were used to construct a Latent Dirichlet Allocation (LDA) Bayesian model. Another 48 MDD patients were used to verify the...
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