Article

Synthetic Routes to Approved Drugs Containing a Spirocycle

2023-04-26

Abstract excerpt

The use of spirocycles in drug discovery and medicinal chemistry has been booming in the last two decades. This has clearly translated in the landscape of approved drugs. Among two dozen clinically used medicines containing a spirocycle, 50% have been approved in the 21st century. The present review focuses on the notable synthetic routes to such drugs invented in industry and academia and is intended to serve as...

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Literature Corpus work: fd593409-306e-5528-901c-8a1d36fa2905
DOI: 10.20944/preprints202304.0933.v1

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