Article
A diversity oriented synthesis of natural product inspired molecular libraries.
Organic & biomolecular chemistry - 7 Nov 2017
Chauhan Jyoti, Luthra Tania, Gundla Rambabu, Ferraro Antonio, Holzgrabe Ulrike, Sen Subhabrata
Abstract excerpt
Natural products are the source of innumerable pharmaceutical drug candidates and also form an important aspect of herbal remedies. They are also a source of various bioactive compounds. Herein we have leveraged the structural attributes of several natural products in building a library of architecturally diverse chiral molecules by harnessing R-tryptophan as the chiral auxiliary. It is converted to its...
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