Article

Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline-1,2, 3-Triazole-Anilines as Potential Antitubercular and Anti-HIV Agents

2025-04-11

Abstract excerpt

HIV/AIDS and Mycobacterial tuberculosis (Mtb) are the leading cause of deaths world-wide. Thus, better medicaments are required to manage these diseases. Quinolines have shown great potential due to their broad spectrum of biological activity. Thus, quinoline-1,2,3-triazole-aniline hybrids were synthesised in moderate to good yields. Compounds 11g (IC50 = 0.388 µM), 11h (IC50 = 0.01032 µM) and 11i (IC50 = 0.167 µM...

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Literature Corpus work: 99a2aa0e-bb3d-5e44-9b7e-4db3d1343851
DOI: 10.20944/preprints202504.0967.v1

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