Article

An optimized toolkit for precision base editing

2018-04-17

Abstract excerpt

CRISPR base editing is a potentially powerful technology that enables the creation of genetic mutations with single base pair resolution. By re-engineering both DNA and protein sequences, we developed a collection of constitutive and inducible base editing vector systems that dramatically improve the ease and efficiency by which single nucleotide variants can be created. This new toolkit is effective in a wide ran...

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Identifiers and source

Literature Corpus work: fd4ce72e-40fe-5d95-a133-2ca7a606fb3c
DOI: 10.1101/303131

Open publication

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