Article

Syngeneic model of carcinogen-induced tumor mimics basal/squamous, stromal-rich, and neuroendocrine molecular and immunological features of muscle-invasive bladder cancer

2022-12-05

Abstract excerpt

<h4>Background</h4> Bladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors could have impact to drive treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are needed to test novel therapies. Carcinogen-induced bladder cancer models represent heterogeneous, immune-competent, pre-clinical testing options with many fe...

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Literature Corpus work: fd4bdf0f-e06c-521b-9908-d53d81084a7e
DOI: 10.1101/2022.12.03.518865

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