Article

Cell-of-origin and genetic drivers define advanced bladder cancer subtypes and potential therapeutic response in mouse models

2025-07-18

Abstract excerpt

Bladder cancer (BC) remains a major clinical challenge owing to its high recurrence, limited treatment options, and molecular heterogeneity. Despite recent therapeutic advances, prognosis remains poor, and resistance is frequent, underscoring the need for improved experimental models to study tumorigenesis and therapeutic response. A key limitation of advanced BC research is the scarcity of in vivo models that ac...

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Literature Corpus work: dd9c9f4a-6318-5113-90fe-b6a94ea477f1
DOI: 10.1101/2025.07.14.664768

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