Article

Suppression of non-canonical autophagy induces endothelial and cardiac dysfunction

2025-12-18

Abstract excerpt

<h4>Background:</h4> While roles for canonical autophagy in the pathophysiology of cardiovascular disease have been established, we have limited understanding of the non-canonical functions of autophagy proteins in this context. LC3-asssociated endocytosis (LANDO) is a novel non-canonical function of autophagy proteins, in which LC3 (microtubule-associated protein light chain 3) is conjugated to early endosome me...

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Literature Corpus work: fcb480b1-76d8-5c1f-b1f8-8eac46c27ccb
DOI: 10.64898/2025.12.17.695030

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