Article

Comparative <i>in vitro</i> transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes

2020-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Hydroxychloroquine (HCQ) has emerged as a potential and controversial antiviral candidate therapy for COVID-19. While many clinical trials are underway to test the efficacy of HCQ as a treatment for COVID-19, underlying mechanisms of HCQ in the setting of COVID-19 remain unclear. Hence, we examined differential gene expression signatures of HCQ exposure, in vitro SARS-CoV-2 infection, and host...

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Literature Corpus work: fc2fe73f-844f-5e12-a348-9d72bbe403ff
DOI: 10.1101/2020.04.13.039263

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Comparative <i>in vitro</i> transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genesDOI 10.1101/2020.04.13.039263Read

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