Article

Hydroxychloroquine inhibits trained immunity – implications for COVID-19

2020-06-09

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 infection can cause severe disease for which currently no specific therapy is available. The use of hydroxychloroquine to prevent or treat SARS-CoV-2 infection is controversial and its mode of action poorly understood. We demonstrate that hydroxychloroquine inhibits trained immunity at the functional and epigenetic level and is accompanied by profound changes in the cellular lipidome a...

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Literature Corpus work: e6157266-edd5-506d-86fa-c0964636015a
DOI: 10.1101/2020.06.08.20122143

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