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Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma

2022-10-13

Abstract excerpt

<h4>Background</h4> Non-enhancing (NE) infiltrating tumor cells beyond the contrast-enhancing (CE) bulk of tumor are potential propagators of recurrence after gross total resection of high-grade glioma. <h4>Methods</h4> We leveraged single-nucleus RNA-sequencing on 15 specimens from 5 high grade gliomas to compare prospectively identified biopsy specimens acquired from CE and NE regions. Additionally, 24 CE and...

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Literature Corpus work
fc29d518-0558-5c43-8ee6-4f3687067708
DOI
10.1101/2022.10.10.511639
Open publication

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Single-nucleus expression characterization of non-enhancing region of recurrent high-grade gliomaDOI 10.1101/2022.10.10.511639
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