Article

Association of ACE2 Polymorphisms and Derived Haplotypes with Obesity and Hyperlipidemia in Female Spanish Adolescents

2021-12-21

Abstract excerpt

<h4>Background: </h4> In the cardiovascular (CV) system, overactivation of the angiotensin converting enzyme (ACE) may trigger deleterious responses derived from angiotensin (Ang)-II, which can be attenuated by stimulation of ACE2 and subsequent Ang-(1-7) metabolite. However, ACE2 exhibits a high degree of genetic polymorphism that may affect its structure and stability, interfering with these cardioprotective act...

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Literature Corpus work: fc1e3852-b46c-5287-8521-e44a44f491b7
DOI: 10.21203/rs.3.rs-968623/v2

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