Article
Angiotensin converting enzyme insertion/deletion polymorphism is associated with increased adiposity and blood pressure in obese children and adolescents.
Gene - 15 Dec 2013
Lemes Vinícius A F, Neves Ana Luísa, Guazzelli Isabel C, Frazzatto Eliana, Nicolau Christiane, Corrêa-Giannella Maria Lúcia, Velho Gilberto, Villares Sandra M F
Abstract excerpt
BACKGROUND: The insertion/deletion polymorphism in the gene encoding the angiotensin-converting enzyme (ACE I/D) was associated with arterial hypertension and obesity in adults, but the data in children are scarce and yielded contrasting results. We assessed the impact of the ACE I/D on blood pressure and obesity related traits in a Brazilian cohort of obese children and adolescents. METHODS AND RESULTS: ACE I/D...
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