Association of ACE2 genetic variants with blood pressure, left ventricular mass, and cardiac function in Caucasians with type 2 diabetes.

doi:10.1038/ajh.2011.188

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Article

Association of ACE2 genetic variants with blood pressure, left ventricular mass, and cardiac function in Caucasians with type 2 diabetes.

American journal of hypertension - 1 Feb 2012

Patel Sheila K, Wai Bryan, Ord Michelle, MacIsaac Richard J, Grant Sharon, Velkoska Elena, Panagiotopoulos Sianna, Jerums George, Srivastava Piyush M, Burrell Louise M

Abstract excerpt

BACKGROUND: Cardiovascular disease is common in diabetes, and is associated with activation of the renin-angiotensin system (RAS). Angiotensin-converting enzyme (ACE)2 is a recently described member of the RAS, and this study investigated whether ACE2 polymorphisms are associated with hypertension, left ventricular (LV) mass, and cardiac function in type 2 diabetes. METHODS: Variants in ACE2 (rs1978124,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21993363
DOI: 10.1038/ajh.2011.188

Genes

ACE2
ACE

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