Article
Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population.
BMC cardiovascular disorders - 11 Mar 2013
Al-Najai Mohammed, Muiya Paul, Tahir Asma I, Elhawari Samar, Gueco Daisy, Andres Editha, Mazhar Nejat, Altassan Nada, Alshahid Maie, Dzimiri Nduna
Abstract excerpt
BACKGROUND: Angiotensinogen (AGT) constitutes a central component of the renin-angiotensin system that controls the systemic blood pressure and several other cardiovascular functions and may play an important role in atherosclerosis pathways. In this study, we employed TaqMan genotyping assays to evaluate the role of 8 AGT variants in primary hypertension (HTN), type 2 diabetes mellitus (T2DM), and obesity as a...
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