Article

Discovering Broader Host Ranges and an IS-bound Prophage Class Through Long-Read Metagenomics

2025-05-10

Abstract excerpt

Gut bacteriophages profoundly impact microbial ecology and human health, yet they are greatly understudied. Using deep, long-read bulk metagenomic sequencing, a technique that overcomes fundamental limitations of short-read approaches, we tracked prophage integration dynamics in 12 longitudinal stool samples from six healthy individuals, spanning a two-year timescale. While most prophages remain stably integrated...

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Literature Corpus work: fb8128ee-6899-56a9-b9a7-0193f4121400
DOI: 10.1101/2025.05.09.652943

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