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Prevalent Gut Phages Encode Modular Adhesins Mediating Epithelial Binding and Endoplasmic Reticulum Trafficking

2026-02-02

Abstract excerpt

Bacteriophages are crucial components of the human microbiome and hold promise as therapeutic agents. Yet, their physical interactions with mammalian cells remain poorly understood. Here, we developed a high-throughput platform to identify phages that adhere to epithelial layers and the proteins that mediate this interaction. The identified phages encode immunoglobulin (Ig)-like domain-containing proteins that, wh...

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Literature Corpus work
e4b7caff-ec15-5d9a-8a81-6985fd9ab901
DOI
10.64898/2026.02.02.702849
Open publication

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Prevalent Gut Phages Encode Modular Adhesins Mediating Epithelial Binding and Endoplasmic Reticulum TraffickingDOI 10.64898/2026.02.02.702849
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