Article

Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome

2024-11-16

Abstract excerpt

Transducing bacteriophages and gene transfer agents (GTA) are constrained by their capsids’ structural properties in the length of host DNA they can package. Nanopore sequencing of intact capsid-packaged DNA molecules with full-sized reads can be used to establish the precise lengths and identity of individual packaged DNA molecules and their association with specific bacterial hosts. This approach was validated u...

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Literature Corpus work: 176af9d9-5790-5b6a-b516-3a8da0436fd5
DOI: 10.1101/2024.11.15.623857

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