Article

<i>Microbe-seq</i> : high-throughput, single-microbe genomics with strain resolution, applied to a human gut microbiome

2020-12-14

Abstract excerpt

We present Microbe-seq , a high-throughput single-microbe method that yields strain-resolved genomes from complex microbial communities. We encapsulate individual microbes into droplets with microfluidics and liberate their DNA, which we amplify, tag with droplet-specific barcodes, and sequence. We use Microbe-seq to explore the human gut microbiome; we collect stool samples from a single individual, sequence ov...

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Literature Corpus work: d779e13c-2eb4-5867-9b41-c6447c1ccf48
DOI: 10.1101/2020.12.14.422699

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