Article

A prevalent huge phage clade in human and animal gut microbiomes

2025-08-11

Abstract excerpt

Huge phages are widespread in the biosphere, yet their prevalence and ecology in the human gut remain poorly characterized. Here, we report Jug (Jumbo gut) phages with genomes of 360-402 kilobase pairs that comprise ~1.1% of the reads in human gut metagenomes, and are predicted to infect Bacteroides and/or Phocaeicola. Although three of the four major groups of Jug phages shared >90% genome-wide sequence identity,...

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Literature Corpus work: 9284226f-c84e-5657-9b53-d896edca4b9b
DOI: 10.1101/2025.08.10.669567

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