Article

MYRF is Essential for Epicardial Development

2025-10-17

Abstract excerpt

<h4>SUMMARY</h4> Myelin Regulatory Factor (MYRF) is a transcription factor previously known for myelination of neurons in the central nervous system. Accumulating evidence has recently implicated MYRF mutations in the pathogenesis of cardiac urogenital syndrome (CUGS), in which patients exhibit a range of cardiac abnormalities, including atrial septal defect (ASD), ventricular septal defect (VSD), and hypoplasti...

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Literature Corpus work: fc144b0d-e8a1-5199-ab41-bb7171e334b6
DOI: 10.1101/2025.10.17.682841

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