Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy

1 Jan 2012

Abstract excerpt

CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system, we report the in vivo disruption of CENP-F gene function in murine cardiomyocytes, a cell type displaying high levels of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Congenital heart defects research
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22563055
DOI: 10.1242/dmm.008680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathyPMID 22563055Read ↗

Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.Semantic proximity Read ↗

Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in miceSemantic proximity Read ↗

Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death.Semantic proximity Read ↗

Repression of <i>Pdzrn3</i> is required for heart maturation and protects against heart failureSemantic proximity Read ↗

Tafazzin Knockdown in Mice Leads to a Developmental Cardiomyopathy With Early Diastolic Dysfunction Preceding Myocardial NoncompactionSemantic proximity Read ↗

Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated CardiomyopathySemantic proximity Read ↗

Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors Is Required for Cardiomyocyte Integrity in Load-Induced Ventricular HypertrophySemantic proximity Read ↗

Cytoskeletal defects in cardiomyopathy.Semantic proximity Read ↗

Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy.Semantic proximity Read ↗

Lem2 is essential for cardiac development by maintaining nuclear integritySemantic proximity Read ↗

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesisSemantic proximity Read ↗

Lem2 is essential for cardiac development by maintaining nuclear integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.