Article

Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit <i>Aedes aegypti</i> populations

2019-04-12

Abstract excerpt

<h4>Background</h4> The discovery of CRISPR-based gene editing and its application to homing-based gene drive systems has been greeted with excitement, for its potential to control mosquito-borne diseases on a wide scale, and concern, for the invasiveness and potential irreversibility of a release. Gene drive systems that display threshold-dependent behavior could potentially be used during the trial phase of thi...

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Literature Corpus work: fbe005a3-d3b1-51a2-b085-7a02a225dcdb
DOI: 10.1101/607267

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