Article

Gene Drives Across Engineered Fitness Valleys: Modeling a Design to Prevent Drive Spillover

2020-10-29

Abstract excerpt

1 Engineered gene drive techniques for population replacement and/or suppression have potential for tackling complex challenges, including reducing the spread of diseases and invasive species. Unfortunately, the self-propelled behavior of drives can lead to the spread of transgenic elements beyond the target population, which is concerning. Gene drive systems with a low threshold frequency for invasion, such as ho...

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Literature Corpus work: 64a475f5-6978-5eba-b250-55df8fb6a1ef
DOI: 10.1101/2020.10.29.360404

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