Article

Development of a Novel Human CD147 Transgenic NSG Mouse Model to test SARS-CoV-2 Infection and Immune Responses

2021-04-07

Abstract excerpt

<title>Abstract</title> <p>An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the newly emerged, rapidly spreading SARS-CoV-2 and development of therapeutic strategies. Studies show that the spike (S) proteins of SARS-CoV (SARS-CoV-S-1-S) and SARS-CoV-2 (SARS-CoV-2-S) bind to human angiotensin-converting enzyme 2 (hACE2, a well-recognized, functional receptor for SARS-C...

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Literature Corpus work: fbae5e29-19d1-50bb-9eee-4372e6e8cb0f
DOI: 10.21203/rs.3.rs-396257/v1

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