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Brequinar and Dipyridamole in Combination Exhibits Synergistic Antiviral Activity Against SARS-CoV-2 <i>in vitro</i> : Rationale for a host-acting antiviral treatment strategy for COVID-19

2022-03-31

Abstract excerpt

<h4>ABSTRACT</h4> The continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has compromised the efficacy of currently available vaccines and monoclonal antibody (mAb)-based treatment options for COVID-19. The limited number of authorized small-molecule direct-acting antivirals present challenges with pill burden, the necessity for intravenous administration or potential drug interact...

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Literature Corpus work: fb723c34-e4eb-580e-9e9f-e959186b07cd
DOI: 10.1101/2022.03.30.486499

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Brequinar and Dipyridamole in Combination Exhibits Synergistic Antiviral Activity Against SARS-CoV-2 <i>in vitro</i> : Rationale for a host-acting antiviral treatment strategy for COVID-19DOI 10.1101/2022.03.30.486499Read

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