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Nucleotide and nucleoside-based drugs: past, present, and future

31 Oct 2022

Abstract excerpt

Nucleotide and nucleoside-based analogue drugs are widely used for the treatment of both acute and chronic viral infections. These drugs inhibit viral replication due to one or more distinct mechanisms. It modifies the virus's genetic structure by reducing viral capacity in every replication cycle. Their clinical success has shown strong effectiveness against several viruses, including ebolavirus, hepatitis C...

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PMID: 36389209
DOI: 10.1016/j.sjbs.2022.103481

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