Article
A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1.
BMC systems biology - 19 Oct 2010
Sigurdsson Martin I, Jamshidi Neema, Steingrimsson Eirikur, Thiele Ines, Palsson Bernhard Ø
Abstract excerpt
BACKGROUND: Well-curated and validated network reconstructions are extremely valuable tools in systems biology. Detailed metabolic reconstructions of mammals have recently emerged, including human reconstructions. They raise the question if the various successful applications of microbial reconstructions can be replicated in complex organisms. RESULTS: We mapped the published, detailed reconstruction of human...
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