Article
The “adductome”: a limited repertoire of adducted proteins in human cells
2019-12-11
Abstract excerpt
<h4>ABSTRACT</h4> Proteins form adducts with nucleic acids in a variety of contexts, and these adducts may be cytotoxic if not repaired. Here we apply a proteomic approach to identification of proteins adducted to DNA or RNA in normally proliferating cells. This approach combines RADAR fractionation of proteins covalently bound to nucleic acids with quantitative mass spectrometry (MS). We demonstrate that “RADAR-...
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Identifiers and source
- Literature Corpus work
- fb48dd04-a93c-584c-85e1-89a5c66d15a1
- DOI
- 10.1101/872176