Article

Oncoprotein GT198 is a direct target of taxol

2019-06-19

Abstract excerpt

<h4>ABSTRACT</h4> Taxol (paclitaxel) is one of the most successful chemotherapeutic drugs in the treatment of human cancer. It has recently been questioned whether the mechanism of action in mitotic arrest, which is ubiquitously present in all cells, is sufficient to explain the tumor specificity, clinical efficacy, and side effects of taxol. In this report, we have identified a new protein target of taxol as GT1...

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Literature Corpus work: fb399cd5-6515-54c5-9b82-385c7e8ebff1
DOI: 10.1101/675579

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