Article
Coiled-coil motif as a structural basis for the interaction of HTLV type 1 Tax with cellular cofactors.
AIDS research and human retroviruses - 1 Nov 2000
Chun A C, Zhou Y, Wong C M, Kung H F, Jeang K T, Jin D Y
Abstract excerpt
Human T lymphotropic virus type 1 (HTLV-1) Tax is a multifunctional protein centrally involved in transcriptional regulation, cell cycle control, and viral transformation. The regulatory functions of Tax are thought to be mediated through protein-protein interaction with cellular cofactors. Previously we have identified several novel binding partners for Tax, including human mitotic checkpoint protein MAD1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
