Article

SARS-CoV-2 infection activates endogenous retroviruses of the LTR69 subfamily

2023-03-21

Abstract excerpt

Accumulating evidence suggests that endogenous retroviruses (ERVs) play an important role in the host response to infection and the development of disease. By combining RNA- and ChIP-sequencing analyses with RT-qPCR, we show that SARS-CoV-2 infection induces the LTR69 subfamily of ERVs, both in vitro and in vivo . Using functional assays, we identified one SARS-CoV-2-activated LTR69 locus, termed Dup69, which ex...

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Literature Corpus work: fb2d5949-8b30-5dc8-be82-994b5fcb08ba
DOI: 10.1101/2023.03.21.533610

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