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Article

SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elements

3 Nov 2021

Abstract excerpt

SARS-CoV-2 promotes an imbalanced host response that underlies the development and severity of COVID-19. Infections with viruses are known to modulate transposable elements (TEs), which can exert downstream effects by modulating host gene expression, innate immune sensing, or activities encoded by their protein products. We investigated the impact of SARS-CoV-2 infection on TE expression using RNA-Seq data from...

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PMID: 34731091
DOI: 10.1172/jci.insight.147170

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