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LRH-1 Ameliorates Hepatic Triglyceride Accumulation via Regulation of Perilipin 5 in the Liver

2021-02-11

Abstract excerpt

Liver receptor homolog-1 (LRH-1) has emerged as a regulator of hepatic glucose, bile acid, and mitochondrial metabolism. However, the functional mechanism underlying the effect of LRH-1 on lipid mobilization has not been addressed. This study investigated the regulatory function of LRH-1 in lipid metabolism during fasting. The wild-type (WT) and LRH-1 liver-specific knockout (LKO) mice were either fed or fasted fo...

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Literature Corpus work
fb293b0e-f625-59d0-b98b-d0a25477051a
DOI
10.20944/preprints202102.0276.v1
Open publication

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LRH-1 Ameliorates Hepatic Triglyceride Accumulation via Regulation of Perilipin 5 in the LiverDOI 10.20944/preprints202102.0276.v1
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