Article

Polygenicity and prevalence contribute to investigating the genetic signature of common diseases

2023-11-20

Abstract excerpt

It was a great challenge in searching for the pathogenic genes of complicated disorders that are deleterious to human health. To search for characterized genetic signatures of common diseases, we developed a causal genotype combination pattern (CGCP) program previously. In this study, we used mathematics formula to infer the theoretical existence of linear relationship between variants frequency and prevalence, th...

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Literature Corpus work: fb17ea10-6561-52fc-93d2-a237149dbf5a
DOI: 10.21203/rs.3.rs-3620592/v1

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