Article
A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese.
PloS one - 1 Jan 2015
Yin Xianyong, Cheng Hui, Lin Yan, Wineinger Nathan E, Zhou Fusheng, Sheng Yujun, Yang Chao, Li Pan, Li Feng, Shen Changbing, Yang Sen, Schork Nicholas J, Zhang Xuejun
Abstract excerpt
With numbers of common variants identified mainly through genome-wide association studies (GWASs), there is great interest in incorporating the findings into screening individuals at high risk of psoriasis. The purpose of this study is to establish genetic prediction models and evaluate its discriminatory ability in psoriasis in Han Chinese population. We built the genetic prediction models through weighted...
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