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Article

Genome‑wide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan.

Molecular medicine reports - 1 Jul 2024

Yang Jai-Sing, Liu Ting-Yuan, Lu Hsing-Fang, Tsai Shih-Chang, Liao Wen-Ling, Chiu Yu-Jen, Wang Yu-Wen, Tsai Fuu-Jen

Abstract excerpt

Psoriasis is a chronic inflammatory dermatological disease, and there is a lack of understanding of the genetic factors involved in psoriasis in Taiwan. To establish associations between genetic variations and psoriasis, a genome‑wide association study was performed in a cohort of 2,248 individuals with psoriasis and 67,440 individuals without psoriasis. Using the ingenuity pathway analysis software, biological...

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Identifiers

PMID: 38757301
DOI: 10.3892/mmr.2024.13239
PMCID: PMC11106694

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