Article

CHESS 3: an improved, comprehensive catalog of human genes and transcripts based on large-scale expression data, phylogenetic analysis, and protein structure

2022-12-22

Abstract excerpt

The original CHESS database of human genes was assembled from nearly 10,000 RNA sequencing experiments in 53 human body sites produced by the Genotype-Tissue Expression (GTEx) project, and then augmented with genes from other databases to yield a comprehensive collection of protein-coding and noncoding transcripts. The construction of the new CHESS 3 database employed improved transcript assembly algorithms, a new...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b085d82c-e947-59f1-a0a6-f3080b927112
DOI: 10.1101/2022.12.21.521274

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CHESS 3: an improved, comprehensive catalog of human genes and transcripts based on large-scale expression data, phylogenetic analysis, and protein structureDOI 10.1101/2022.12.21.521274Read

Thousands of large-scale RNA sequencing experiments yield a comprehensive new human gene list and reveal extensive transcriptional noiseSemantic proximity Read

A pan-tissue, pan-disease compendium of human orphan genesSemantic proximity Read

Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses.Semantic proximity Read

SC2disease: a manually curated database of single-cell transcriptome for human diseases.Semantic proximity Read

Nearly all new protein-coding predictions in the CHESS database are not protein-codingSemantic proximity Read

Highly accurate isoform identification for the human transcriptomeSemantic proximity Read

The RNA Atlas, a single nucleotide resolution map of the human transcriptomeSemantic proximity Read

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.Semantic proximity Read

Thousands of exon skipping events differentiate among splicing patterns in sixteen human tissuesSemantic proximity Read

Transcriptome variation in human tissues revealed by long-read sequencingSemantic proximity Read

SCOTCH: isoform-level characterization of gene expression through long-read single-cell RNA sequencingSemantic proximity Read

Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals.Semantic proximity Read